Products for prevention of RSV (updated 9/17/24 with 2024 news!)

Last year was the first time we had options for protection from RSV. A vaccine during pregnancy, or an antibody given directly to baby after birth. Generally only one or the other would be given, not both.

RSV info:

Updated slides

For infants under 8 months:

Nirsevimab (Beyfortus) is a monoclonal antibody that provides protection to the baby for as long as the antibody is circulating, which is thought to be at least 5 months. Babies should receive a single dose of 50 mg or 100 mg depending on their weight.

This product is included in Washington’s Childhood Vaccine Program.

For babies 8-19 months:

Some children should receive a dose of nirsevimab in their second RSV season:

  • Children with chronic lung disease of prematurity who required medical support (chronic corticosteroid therapy, diuretic therapy or supplemental oxygen) any time during the 6-month period before the start of the second RSV season. 

  • Children who are severely immunocompromised.  

  • Children with cystic fibrosis who have manifestations of severe lung disease (previous hospitalization for pulmonary exacerbation in the first year of life or abnormalities on chest imaging that persist when stable) or have weight-for-length that is <10th percentile. 

  • American Indian and Alaska Native children (note that this is a new group for whom second-season prophylaxis is recommended in contrast to the current palivizumab recommendations).  

These children should receive 2 x 100 mg, so the codes would be 2 units of CPT 90381 with Diagnosis (ICD10) Z29.11.


For pregnant people:

Abrysvo is a vaccine given to pregnant people between 32-36 weeks gestation, with the goal of producing antibodies to be exported to baby, so they’re born pre-stocked with antibodies against RSV. Abrysvo is currently available in pharmacies. Caution: there is a different RSV vaccine for older adults, Arexvy, that is NOT approved for pregnancy. If you get vaccinated at a pharmacy, confirm with your own eyes that you’re receiving Abrysvo, not Arexvy.

Codes to ask about:

CPT 90678 Abrysvo RSV vaccine with Diagnosis (ICD10) Z23 and a code specific to your week of gestation (Z3A.33, Z3A.34, Z3A.35, or Z3A.36)


Read more:

RSV: What Parents of Young Children Should Know (CDC)

RSV: New tools for prevention (AAP)

Free webinar for parents on RSV prevention strategies October 6, 2023 (AAP, sanofi)

Elias Kass